Benefits Of Calcium Orotate

Calcium orotate is a highly usable form of calcium supplement due to the particular abilities of the molecule calcium is bound to in this preparation. That molecule is called orotic acid, and when calcium combines with it, a mineral salt is made which "penetrates the outer cell membrane ... and is only metabolized at the site of the membranes of the mitochondria and of the structures found in the cell plasma. Only here the mineral will be released to the form of an ion." (biomedx.com)

What this is saying is that the calcium in calcium orotate supplements is carried directly into the cell, and is deposited deeper into the cell compared to other types of biological transports. The above article was discussing orotic acid compared to AEP (2-aminoethylphosphoric acid) and aspartic acid, though these are not necessarily what is used in other types of calcium supplements, which commonly use mineral aspartates and other carriers.

Dr Hans Nieper

This information is taken from articles by Dr Hans Nieper, a German doctor who used these types of supplements in his clinic. Dr Nieper passed away in 1998. He was known as an oncologist and cardiologist, although he also had experience in treating patients with MS. Whilst he was a German clinician who didn't really write and publish material in medical journals, he was known worldwide for his more unconventional work in these areas.

It's important to note that Dr Nieper was not a mainstream doctor in terms of the accepted ideologies regarding the areas he practiced in. And there are not really clinical trials to back up his work, as it was ignored by mainstream medical science for many years.

However, it would be wrong to simply dismiss him as a 'quack'. He was a legitimate doctor who actually worked with patients, as opposed to simply research. And he had success with many, as did those colleagues who used his ideas on their own patients.

There are some great articles on Dr Nieper here, and here.

"Dr. Nieper's patients included many world stars, royalty and politicians: Anthony Quinn, John Wayne, Yul Brynner, William Holden and Princess Caroline of Monaco. He advised the ailing ex-president Ronald Reagan. But more importantly, he treated thousands of everyday people like you and me. Nancy Sinatra lavished praise on this great German physician: "He is a fabulous person, a recognized scientist, a marvelous doctor." His patients both loved and respected him."

Is his hypothesis on calcium orotate and other mineral transporters correct? I'll quote two sources, and let you make up your own mind:

"Ultimately the value of Nieper’s work on mineral transporters does not depend upon whether his theories and explanations were valid, or upon whether his observations were biased, or upon the rulings of the government or the medical cartel. It depends only upon whether the transporters work when you use them. Many users are quite convinced that their lives or health have been rescued by these supplements, and this alone justifies their existence in the marketplace."
(delano.com)

"For now I'll just state my summary conclusions: There is independent scientific evidence corroborating Nieper's theory of orotates as mineral transporters. In my judgment, the evidence tends to support Nieper's criteria for orotate as an electrolyte carrier, namely, (1) a low dissociation constant, (2) an affinity for specific cellular systems or organs, and (3) a metabolic pathway which liberates the transported mineral within the targeted organ or system. [1]" oasisadvancedwellness.com

Calcium Orotate

Dr Nieper believed, based primarily on medical intuition and his experience with, and observation of his own patients, that:

Calcium orotate protects the body from arteriosclerosis

Calcium orotate is able to be utilized by people who have problems with calcium metabolism due to a defective transport system into their own cells.

Calcium orotate has a beneficial effect on cartilage tissue and all tissue that uses the pentose pathway. Parts of the body that use the pentose pathway, which is a form of cellular metabolism, include:

cartilage
ligaments
connective tissue
skin
walls of blood vessels
part of the veins in the blood-brain barrier
part of the heart tissue relating to stimulation and regulation
hair, nails and other keratin related tissue
bone
heart muscle
and in liver cells and the stroma.

Calcium orotate is great for decalcification in the spine, having been used in some very serious spinal bone injuries in Germany with success. It's also great for fractures, and has been used in Germany for various bone related diseases like osteochondrosis, Bechterew disease, osteoporosis, disk degeneration, and recalcification of bone in cancers with bone metastases.

Calcium orotate prevents cortisone side effects with regards cartilage damage: "The orotic acid plays a very important role to so-called pentose pathway metabolism which accounts for the metabolism in cartilage tissue and especially for all organs which account for aging. There, the ribose coupling needs orotic add and therefore obviously the orotic carrying molecule has a high affinity to this kind of tissue, like cartilage which, so far, we were unable to influence and which experienced even more damage under the influence of cortisone. Therefore, calcium orotate seems to me to be one of the most important substances to prevent cortisone side effects in, eg, rheumatoid arthritis. This is very important." (biomedx.com)

Calcium orotate had a beneficial effect on the liver:

"Four patients who had taken, on the average, 3g of calcium orotate in stomach acid resistant capsules per day, for more than a year, submitted to a liver puncture. (For reasons which had nothing to do with the application of calcium orotate.) In all cases there was no sign of fatty liver development. Quite the contrary, three of the patients with stage 3 fatty liver showed a remarkable improvement under long term calcium orotate therapy." (alkalizeforhealth.net )

Calcium orotate is beneficial in relieving angina pains